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(−)-Deguelin

(−)-Deguelin
(−)-Deguelin
Product Code : 560
Product Description

(−)-Deguelin

  • Synonym: (7aS,13aS)-13,13a-Dihydro-9,10-dimethoxy-3,3-dimethyl-3H-bis[1]benzopyrano[3,4-b:6,5-e]pyran-7(7aH)-one

    • Empirical Formula (Hill Notation): C23H22O6

    • Molecular Weight: 394.42

    • CAS Number: 522-17-8

 assay  


>98% (HPLC)
form   powder
optical activity   [α]/D -70 to -80°, c = 0.2 in methanol
color   white to beige
mp   85-87 °C(lit.)
solubility   DMSO: soluble10 mg/mL, clear
storage temp.   20°C

Description

Biochem/physiol Actions

Inhibitor of activated Akt. Does not affect MAPK, ERK1/2, or JNK. Anticancer, chemoprotective agent.


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