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(E)-Guggulsterone

(E)-Guggulsterone
(E)-Guggulsterone
Product Code : 166
Product Description

(E)-Guggulsterone

Analytical standard

Synonym: (17E)-Pregna-4,17(20)-diene-3,16-dione

  • CAS Number 39025-24-6

  • Empirical Formula (Hill Notation) C21H28O2

  • Molecular Weight 312.45

grade   analytical standard
assay   ≥95.0% (HPLC)
form   neat
shelf life   limited shelf life, expiry date on the label
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
format   neat

Biochem/physiol Actions

Naturally occuring bioactive plant sterol isolated from the gum resin of guggul (Commiphora wightii). Antihyperlipidemic. Induces the expression of human CYP3A.[]. Guggulsterone potently reverses multi-drug resistance in a number of human cancer cell lines, extending the efficacy of chemotherapy.[]

 


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