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(+)-Norfenfluramine hydrochloride

(+)-Norfenfluramine hydrochloride
(+)-Norfenfluramine hydrochloride
Product Code : 553
Product Description

(+)-Norfenfluramine hydrochloride

  • Synonym: JP 92, NSC 43036, S-(+)-α-Methyl-3-(trifluoromethyl)benzeneethanamine hydrochloride

    • Empirical Formula (Hill Notation): C10H12F3N · HCl

    • Molecular Weight: 239.67

    • CAS Number: 37936-89-3

 assay  


98% (HPLC)
form   powder
drug control   regulated under CDSA - not available from Sigma-Aldrich Canada
color   white
solubility   H2O: >10 mg/mL
storage temp.   2-8°C

Description

Biochem/physiol Actions

(+)-Norfenfluramine is the major hepatic metabolite of (+)-fenfluramine and is primarily responsible for the anorexic effect, as well as side effects; (+)-norfenfluramine causes vasoconstriction and a blood pressure increase in rats with normal blood; acts primarily on the cytoplasmic pool of serotonin; more potent than fenfluramine at inducing dopamine release.

Features and Benefits

This compound is also offered as part of Sigmas Library of Pharmacologically Active Compounds (LOPAC), a biologically annotated collection of high-quality, ready-to-screen compounds.

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