|Home||» Products||» Biochemical & Reagents||» (S)-(−)-Sulpiride|
Synonym: (S)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide, Levosulpiride
Empirical Formula (Hill Notation): C15H23N3O4S
Molecular Weight: 341.43
CAS Number: 23672-07-3
|Gene Information|| human ... DRD2(1813), DRD3(1814)|
rat ... Adra1a(29412), Drd2(24318), Drd3(29238), Htr1a(24473), Htr2a(29595)
D2 dopamine receptor antagonist; antipsychotic.
(S)-(âˆ’)-Sulpiride or Levosulpiride blocks the inhibitory enteric D2 receptors (neuronal and muscular). It has prokinetic activity and is effective in the treatment of functional dyspepsia and gastroparesis in insulin-dependent diabetes mellitus patients.7,8 Since dopamine controls human sexual function, (S)-(âˆ’)-Sulpiride is reportedly effective in treatment of erectile dysfunctions.9
5, 10 g in poly bottle
(S)-(âˆ’)-Sulpiride was used to study the effect of dopamine D2 receptor function on activation of KCNQ potassium channels10 and on depression-like behavior in ovariectomized female rats.11
This compound is also offered as part of Sigmaâ€²s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds.This compound was developed by Sanofi Aventis
NATIONAL ANALYTICAL CORPORATION All Rights Reserved.