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Synonym: (±)-5-(Aminosulfonyl)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide, (±)-N-1-(Ethylpyrrolidin-2-ylmethyl)-2-methoxy-5-sulfamoylbenzamide
Empirical Formula (Hill Notation): C15H23N3O4S
Molecular Weight: 341.43
CAS Number: 15676-16-1
|solubility|| 45% (w/v) aq 2-hydroxypropyl-Î²-cyclode|
|0.1 M HCl: soluble|
|H2O: slightly soluble|
|Gene Information||human ... CA1(759), CA2(760), CA4(762), CA5A(763), CA5B(11238), CA9(768), DRD2(1813)|
Solutions may be stored for several days at 4 °C.
(±)-Sulpiride was used to study the effect of dopamine D2 receptor signaling on calcium channels in rat pituitary melanotropic cells.47
(±)-Sulpiride is a D2 dopamine antagonist and an effective treatment for schizophrenia when used in combination with clozapine, a relatively weak D2-dopaminergic antagonist. It is an antipsychotic agent and also exhibits neuroleptic properties but poorly penetrates the central nervous system.45,46
This compound is also offered as part of Sigmas Library of Pharmacologically Active Compounds (LOPAC), a biologically annotated collection of high-quality, ready-to-screen compounds.
This compound was developed by Sanofi Aventis.
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