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1,1′-Dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate

1,1′-Dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate
1,1′-Dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate
Product Code : 636
Product Description

1,1′-Dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate

  • Synonym: DiI

    • Empirical Formula (Hill Notation): C59H97ClN2O4

    • Molecular Weight: 933.87

    • CAS Number: 41085-99-8

 product line  


BioReagent
assay   ≥98.0% (TLC)
mp   68 °C (dec.)(lit.)
solubility   DMF: soluble
  DMSO: soluble
  methanol: soluble
fluorescence   λex 550 nm; λem 567 nm in phosphate buffer/SDS pH 7.0
suitability   suitable for fluorescence

Description

Biochem/physiol Actions

Lipophilic carbocyanine dye used primarily for optical recordings of membrane voltage and for studies of membrane fluidity. Retrograde stain for neurons; provides intense, long-lasting staining of live neurons in vivo and in vitro.

Other Notes

Lipophilic fluorescent probe for studying membranes[4][6]

Application

1,1′-Dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate is used for the following applications:
• Preparation of Dil solution[3]
• fluorescent membrane dye[2][1][7]
• Di-I Staining[5]

General description

DiI is a Dye Aye, a chemical with CAS number 41085-99-8. It is a fluorescent lipophilic cationic indocarbocyanine dye, which is usually made as a perchlorate salt. Mostly used for scientific staining purposes, such as single molecule imaging, fate mapping and neuronal tracing (as DiI is retained in the lipid bilayers).


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