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1-Deoxymannojirimycin hydrochloride

1-Deoxymannojirimycin hydrochloride
1-Deoxymannojirimycin hydrochloride
Product Code : 742
Product Description

1-Deoxymannojirimycin hydrochloride

  • Synonym: 1,5-Dideoxy-1,5-imino-D-mannitol hydrochloride

    • Empirical Formula (Hill Notation): C6H13NO4 · HCl

    • Molecular Weight: 199.63

    • CAS Number: 73465-43-7

 

Properties



solubility   H2O: soluble10 mg/mL
Mode of action   enzyme | inhibits
antibiotic activity spectrum   viruses
storage temp.   2-8°C

Description

Packaging

1, 5 mg in glass bottle

10 mg in poly bottle

Application

1-Deoxymannojirimycin (DMM) hydrochloride is an inhibitor of N-linked glycosylation and has antiviral activity. Derivatives of deoxymannojirimycin may have anti-HIV activity. It has been used for treatment of T lymphocytes and to study it′s effect on allogeneic cytotoxic T lymphocytes (CTL)[1]. It is used for studies on Golgi-mediated glycoprotein processing.

Biochem/physiol Actions

1-Deoxymannojirimycin is a mannosidase I inhibitor, alters cell-surface complex carbohydrate structure as assayed by PHA-L binding, and increases high mannose structures as indicated by the increased Con-A binding[1].


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