(+)-Norfenfluramine hydrochloride

About (+)-Norfenfluramine hydrochloride

(+)-Norfenfluramine hydrochloride Synonym: JP 92, NSC 43036, S-(+)--Methyl-3-(trifluoromethyl)benzeneethanamine hydrochloride Empirical Formula (Hill Notation): C10H12F3N HClMolecular Weight: 239.67CAS Number: 37936-89-3 assay 98% (HPLC) form powder drug control regulated under CDSA - not available from Sigma-Aldrich Canada color white solubility H2O: >10mg/mL storage temp. 2-8C Description Biochem/physiol Actions (+)-Norfenfluramine is the major hepatic metabolite of (+)-fenfluramine and is primarily responsible for the anorexic effect, as well as side effects; (+)-norfenfluramine causes vasoconstriction and a blood pressure increase in rats with normal blood; acts primarily on the cytoplasmic pool of serotonin; more potent than fenfluramine at inducing dopamine release. Features and Benefits This compound is also offered as part of Sigmas Library of Pharmacologically Active Compounds (LOPAC), a biologically annotated collection of high-quality, ready-to-screen compounds.