1-[2-(Trifluoromethyl)phenyl]imidazole

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Product Description

1-[2-(Trifluoromethyl)phenyl]imidazole

Synonym: TRIM
- Empirical Formula (Hill Notation): C₁₀H₇F₃N₂
- Molecular Weight: 212.17
- CAS Number: 25371-96-4

Properties


storage temp.	2-8°C
Gene Information	human ... NOS1(4842), NOS2(4843), NOS2B(201288), NOS2C(645740), NOS3(4846)

Description

Biochem/physiol Actions

Potent nitric oxide synthase inhibitor. Because of the putative involvement of nitric oxide in depression and stress syndromes, TRIM was studied for its antidepressant effects, and found to reduce manifestations of stress in an animal model as well as fluoxetine.^[]

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC^®¹²⁸⁰), a biologically annotated collection of high-quality, ready-to-screen compounds.