1-Deoxymannojirimycin hydrochloride

About 1-Deoxymannojirimycin hydrochloride

1-Deoxymannojirimycin hydrochloride Synonym: 1,5-Dideoxy-1,5-imino-D-mannitol hydrochloride Empirical Formula (Hill Notation): C6H13NO4 HClMolecular Weight: 199.63CAS Number: 73465-43-7 Properties solubility H2O: soluble10mg/mL Mode of action enzyme | inhibits antibiotic activity spectrum viruses storage temp. 2-8 Degree C Description Packaging 1, 5 mg in glass bottle 10 mg in poly bottle Application 1-Deoxymannojirimycin (DMM) hydrochloride is an inhibitor of N-linked glycosylation and has antiviral activity. Derivatives of deoxymannojirimycin may have anti-HIV activity. It has been used for treatment of T lymphocytes and to study its effect on allogeneic cytotoxic T lymphocytes (CTL). It is used for studies on Golgi-mediated glycoprotein processing. Biochem/physiol Actions 1-Deoxymannojirimycin is a mannosidase I inhibitor, alters cell-surface complex carbohydrate structure as assayed by PHA-L binding, and increases high mannose structures as indicated by the increased Con-A binding.