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Synonym: 1,5-Dideoxy-1,5-imino-D-mannitol hydrochloride
Empirical Formula (Hill Notation): C6H13NO4 · HCl
Molecular Weight: 199.63
CAS Number: 73465-43-7
|solubility||H2O: soluble10 mg/mL|
|Mode of action||enzyme | inhibits|
|antibiotic activity spectrum||viruses|
1, 5 mg in glass bottle
10 mg in poly bottle
1-Deoxymannojirimycin (DMM) hydrochloride is an inhibitor of N-linked glycosylation and has antiviral activity. Derivatives of deoxymannojirimycin may have anti-HIV activity. It has been used for treatment of T lymphocytes and to study it′s effect on allogeneic cytotoxic T lymphocytes (CTL). It is used for studies on Golgi-mediated glycoprotein processing.
1-Deoxymannojirimycin is a mannosidase I inhibitor, alters cell-surface complex carbohydrate structure as assayed by PHA-L binding, and increases high mannose structures as indicated by the increased Con-A binding.