Plasdone Povidone

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MOQ : 1 Piece

Plasdone Povidone Specification

Molecular Formula
(C6H9NO)n

Storage Instructions
Store in a cool, dry place in tightly closed containers

Size
Various, as per customer requirements

CAS No
9003-39-8

Molecular Weight
variable (dependent on grade; e.g., K30 ~40,000 g/mol)

Physical State
Powder

Shelf Life
5 years

Purity
99%

Density
1.2 Gram per cubic centimeter(g/cm3)

Melting Point
130C 150C (decomposes)

Ph Level
3.0 7.0 (5% solution)

Usage
Used as binder, stabilizer, and dispersant in tablets and granules

Packaging Type
HDPE bag / Drum

Grade
Pharmaceutical Grade

Type
Polyvinylpyrrolidone

Application
Pharmaceutical excipient, binder in tablets, film former

Appearance
White to off-white powder

Purity(%)
99%

Plasdone Povidone Trade Information

Minimum Order Quantity
1 Piece

Payment Terms
Cash Advance (CA), Cash in Advance (CID)

Supply Ability
3 Pieces Per Week

Main Export Market(s)
Western Europe, Australia, South America, Eastern Europe, Middle East, Central America, Asia, North America, Africa

About Plasdone Povidone

Plasdone Povidone

Chemistry: PVP polymers and VP derivatives

Ashland offers a comprehensive range of Plasdone povidones (PVP). Plasdone povidones are a family of water-soluble polymers based on N-vinylpyrrolidone that combine a unique set of properties for application in a wide variety of dosage forms. Plasdone povidones are commonly used as binders for the development of tablet formulations, whether manufactured by wet granulation, dry granulation or direct compression. Plasdone K polymers are used in solid-dispersion formulations to enhance the solubility of active pharmaceutical ingredients and increase bioavailability.

Plasdone povidone C grades are supplied with low pyrogen levels and can increase solubilization or inhibit crystallization in parenteral dosage forms.

The regulatory compliance information for all Ashland products varies by product family and grade. For specific data about the grade you are interested in, please refer to our Excipient Information Package, now called PRD, and the Certificate of Analysis.

Exceptional Solubility and Versatility

Plasdone Povidone stands out for its remarkable solubility in both water and a wide range of organic solvents. This trait, combined with its flexible grades and molecular weights, enables effortless formulation into tablets, powders, and granules, elevating product consistency and uniformity. Its adaptability positions it as a go-to excipient for diverse pharmaceutical applications.

Strict Quality and Purity Standards

Manufactured under stringent quality controls in India, Plasdone Povidone meets pharmaceutical grade standards with over 99% purity. The product maintains low levels of heavy metals (10 ppm) and minimal residue on ignition (0.1%), ensuring the deliverance of safe and reliable excipient performance in sensitive formulations and drug delivery.

Application Benefits in Pharmaceuticals

As a versatile binder, stabilizer, and dispersant, Plasdone Povidone enhances hardness, uniformity, and dispersion in tablet and granule preparations. Its odorless, tasteless, and stable properties make it especially valuable in oral dosage forms, while the availability of multiple grades allows custom tailoring for specific pharmaceutical processes.

FAQ's of Plasdone Povidone:

Q: How is Plasdone Povidone typically used in the pharmaceutical industry?

A: Plasdone Povidone is widely employed as a binder in tablet manufacturing, a film former in coatings, and a stabilizer or dispersant in granules and suspensions, enhancing uniformity and stability in various pharmaceutical formulations.

Q: What are the storage requirements for maintaining Plasdone Povidone's stability?

A: To preserve its quality and efficacy, Plasdone Povidone should be stored in a cool, dry place in tightly closed HDPE bags or drums, away from moisture and direct sunlight.

Q: When should a specific K-value grade be chosen for formulation?

A: The selection of a K-value grade depends on the required viscosity and application; for instance, K30 is ideal for general binder applications, while higher grades like K90 offer greater viscosity for specialized processes.

Q: Where is Plasdone Povidone sourced and supplied from?

A: Plasdone Povidone is supplied and traded from India, meeting international pharmaceutical quality standards and catering to global procurement requirements.

Q: What benefits does Plasdone Povidone provide compared to other binders?

A: Plasdone Povidone offers excellent solubility, high purity (99%), chemical inertness, and flexibility in use, resulting in improved tablet hardness, consistent drug release, and product stability while maintaining safety with minimal impurities.

Q: What is the process of incorporating Plasdone Povidone into tablet formulations?

A: Plasdone Povidone can be directly blended with active ingredients and excipients in powder form or pre-dissolved for wet granulation, acting as a binding agent to ensure uniform tablet structure and durability.

Q: How does the shelf life of Plasdone Povidone support pharmaceutical manufacturing?

A: With a shelf life of five years under recommended storage, Plasdone Povidone ensures long-term supply stability and reduces risks of expiration, aiding efficient inventory management in pharmaceutical production.

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