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(−)-N6-(2-Phenylisopropyl)adenosine

(−)-N6-(2-Phenylisopropyl)adenosine
(−)-N6-(2-Phenylisopropyl)adenosine
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Product Code : 565
Product Description

()-N6-(2-Phenylisopropyl)adenosine

  • Synonym: (R)-N6-(1-Methyl-2-phenylethyl)adenosine, N6-(L-2-Phenylisopropyl)adenosine, R-()-PIA

    • Empirical Formula (Hill Notation): C19H23N5O4

    • Molecular Weight: 385.42

    • CAS Number: 38594-96-6

 form  


solid
potency   1.17 nM Ki for A1 receptors (using [3H]CHA in rat forebrain preparations)
color   white
solubility   H2O: slightly soluble0.3 mg/mL (Solutions may be stored for several days at 4°C.)
  45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble1.6 mg/mL (Solutions may be stored for several days at 4°C.)
storage temp.   2-8°C
Gene Information   human ... ADORA1(134)

Description

Packaging

25 mg in poly bottle

50, 100 mg in glass bottle

Biochem/physiol Actions

A1 adenosine receptor agonist. Affinity for adenosine receptor is approx. 100— that of the (+)-isomer.

Features and Benefits

This compound is also offered as part of Sigmas Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. 

This compound is featured on the Adenosine Receptors page of the Handbook of Receptor Classification and Signal Transduction.

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