Synonym: (R)-N6-(1-Methyl-2-phenylethyl)adenosine, N6-(L-2-Phenylisopropyl)adenosine, R-()-PIA
Empirical Formula (Hill Notation): C19H23N5O4
Molecular Weight: 385.42
CAS Number: 38594-96-6
|potency||1.17 nM Ki for A1 receptors (using [3H]CHA in rat forebrain preparations)|
|solubility||H2O: slightly soluble0.3 mg/mL (Solutions may be stored for several days at 4C.)|
| 45% (w/v) aq 2-hydroxypropyl--cyclode|
|Gene Information||human ... ADORA1(134)|
25 mg in poly bottle
50, 100 mg in glass bottle
A1 adenosine receptor agonist. Affinity for adenosine receptor is approx. 100 that of the (+)-isomer.
This compound is also offered as part of Sigmas Library of Pharmacologically Active Compounds (LOPAC1280), a biologically annotated collection of high-quality, ready-to-screen compounds.This compound is featured on the Adenosine Receptors page of the Handbook of Receptor Classification and Signal Transduction.