(S)-(+)-Camptothecin

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MOQ : 1 Kilograms

(S)-(+)-Camptothecin Specification

Usage
As a result of these efforts, two camptothecin analogs have been approved for cancer therapy: Topotecan (hycamtin) is approved for the treatment of recurring ovarian cancer, small cell lung cancer, and in combination with cisplatin for cervical cancer; irinotecan (camptosar) is prescribed for advanced cancers of the ...

Molecular Formula
C20H16N2O4

Melting Point
275 to 277 °C (527 to 531 °F)

Boiling point
757.0±60.0 °C at 760 mmHg

Molecular Weight
348.352 Grams (g)

Chemical Name
Camptothecin

(S)-(+)-Camptothecin Trade Information

Minimum Order Quantity
1 Kilograms

Payment Terms
Cash in Advance (CID), Cash Advance (CA)

Supply Ability
500 Kilograms KG Per Month

Delivery Time
2-8 Week

Sample Available
Yes

Sample Policy
Sample costs shipping and taxes has to be paid by the buyer

Packaging Details
Carton and Poly Bag.

Main Export Market(s)
Western Europe, Australia, Eastern Europe, Middle East, Central America, Africa, South America, Asia, North America

Main Domestic Market
All India

About (S)-(+)-Camptothecin

(S)-(+)-Camptothecin Empirical Formula (Hill Notation): C20H16N2O4Molecular Weight: 348.35CAS Number: 7689-03-4assay 90% (HPLC) form powder mp 260C (dec.)(lit.) solubility chloroform/methanol (4: 1): soluble5mg/mL Mode of action DNA synthesis | interferes enzyme | inhibits storage temp. 2-8C Gene Information human ... TOP1(7150)mouse ... Prkca(18750)rat ... Sstr2(54305) Description Other Notes 20S isomer Packaging 1 g in glass bottle 100, 250 mg in glass bottle Biochem/physiol Actions (S)-(+)-Camptothecin binds irreversibly to the DNA-topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I and traps the enzyme in a covalent linkage with DNA. The enzyme complex is ubiquinated and destroyed by the 26S proteasome, thus depleting cellular topoisomerase I. Blocks the cell cycle in S-phase at low does and induces apoptosis in a large number of normal and tumor cell lines by cell cycle-dependent and cell cycle-independent processes. Features and Benefits This compound is a featured product for Apoptosis research.

FAQs of (S)-(+)-Camptothecin:

Q: What is the melting point of (S)-(+)-Camptothecin?

A: The melting point of (S)-(+)-Camptothecin is 275 to 277 C (527 to 531 F).

Q: What is the boiling point of (S)-(+)-Camptothecin?

A: The boiling point of (S)-(+)-Camptothecin is 757.060.0 C at 760 mmHg.

Q: What is the molecular weight of (S)-(+)-Camptothecin?

A: The molecular weight of (S)-(+)-Camptothecin is 348.352 grams (g).

Q: What is the molecular formula of (S)-(+)-Camptothecin?

A: The molecular formula of (S)-(+)-Camptothecin is C20H16N2O4.

Q: What are the approved usage applications of (S)-(+)-Camptothecin analogs in cancer therapy?

A: (S)-(+)-Camptothecin analogs, such as Topotecan and Irinotecan, are approved for cancer therapy. Topotecan is used for the treatment of recurring ovarian cancer, small cell lung cancer, and in combination with cisplatin for cervical cancer. Irinotecan is prescribed for advanced cancers.

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