(S)-()-Propranolol hydrochloride

About (S)-()-Propranolol hydrochloride

(S)-()-Propranolol hydrochloride Synonym: (S)-1-Isopropylamino-3-(1-naphthyloxy)-2-propanol hydrochloride Linear Formula: C10H7OCH2CH(OH)CH2NHCH(CH3)2HClMolecular Weight: 295.80CAS Number: 4199-10-4assay 98% (TLC) form powder optical activity []25/D 25.5, c =1.0 in ethanol(lit.) mp 193-195 C(lit.) solubility ethanol: soluble10mg/mL DMSO: <14.5mg/mL H2O: soluble50mg/mL (With heat. Aqueous solutions are most stable at pH 3.0 and decompose rapidly at basic pH. Decomposition is accompanied by discoloration of the solution.) 45% (w/v) aq 2-hydroxypropyl--cyclodextrin: soluble8.0mg/mL originator AstraZeneca storage temp. 2-8C Gene Information human ... ADRB1(153), ADRB2(154), ADRB3(155), HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355) Show Fewer Properties Description Packaging 100, 500 mg in glass bottle Biochem/physiol Actions Active -adrenoceptor blocking enantiomer, as measured by inhibition of isoprenaline-induced tachycardia; Propranolol is also non-specific 5-HT1A, 5-HT1B and 5-HT1C serotonin receptor antagonist. The stereoselective association of mianserin and propranolol with the 5HT1A, 5HT1B and 5HT1C sites may prove useful in the characterization of these sites Features and Benefits This compound is featured on the -Adrenoceptors