()-Thalidomide

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MOQ : 1 Kilograms

()-Thalidomide Specification

Molecular Formula
C13H10N2O4

Melting Point
270 °C

Molecular Weight
258.23 Grams (g)

Chemical Name
()-Thalidomide

Purity(%)
99%

()-Thalidomide Trade Information

Minimum Order Quantity
1 Kilograms

Payment Terms
Cash in Advance (CID), Cash Advance (CA)

Supply Ability
500 Kilograms KG Per Month

Delivery Time
2-8 Week

Sample Available
Yes

Sample Policy
Sample costs shipping and taxes has to be paid by the buyer

Packaging Details
Carton and Poly Bag.

Main Export Market(s)
Western Europe, Australia, Eastern Europe, Central America, Africa, Middle East, South America, Asia, North America

Main Domestic Market
All India

About ()-Thalidomide

()-Thalidomide Synonym: S()-2-(2,6-Dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione Empirical Formula (Hill Notation): C13H10N2O4Molecular Weight: 258.23CAS Number: 841-67-8 assay >98% form solid optical activity []23/D 62.6, c =2 in DMF(lit.) color white solubility DMSO: soluble H2O: insoluble ethanol: insoluble originator Celgene Gene Information human ... LITAF(9516), TNF(7124)mouse ... Nos2(18126)rat ... Nos1(24598) Description Biochem/physiol Actions (-)-Thalidomide selectively inhibits biosynthesis of tumor necrosis factor (TNF-); inhibitor of angiogenesis. (S)-Thalidomide is a teratogenic enatiomer. Packaging 10 mg in poly bottle 25, 100 mg in glass bottle Preparation Note (-)-Thalidomide is soluble in DMSO, but is insoluble in water and ethanol. Application Thalidomide has been used to study its teratogenic effects in chicken embryos and human embryonic cells. This study reported that thalidomide causes limb defects by stabilizing PTEN, inhibiting the expression of Akt and activating caspase-dependent apoptosis[1]. Thalidomide has also been used for studying glutathione mediated teratogenic resistance in mouse embryos[2]. Features and Benefits This compound was developed by Celgene.