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Home | » Products | » Biochemical & Reagents | » (−)-trans-(1S,2S)-U-50488 hydrochloride hydrate |
Synonym: trans-(1S,2S)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide hydrochloride hydrate
Empirical Formula (Hill Notation): C19H26Cl2N2O · HCl · xH2O
Molecular Weight: 405.79 (anhydrous basis)
CAS Number: 114528-79-9 (anhydrous)
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≥98% (HPLC) | |
form | solid |
optical activity | [α]22/D −36.05°, c = 0.73 in methanol(lit.) |
storage condition | desiccated |
color | white |
solubility | H2O: soluble13 mg/mL |
storage temp. | 2-8°C |
Gene Information | human ... OPRK1(4986) |
Potent κ opioid receptor agonist; more potent enantiomer of (±)-trans-U-50488.
(−)-trans-(1S,2S)-U-50488 hydrochloride hydrate is soluble in water at 13 mg/ml.
(−)-trans-(1S,2S)-U-50488 hydrochloride hydrate (U-50488) has been used as a κ-opioid receptor (KOR) agonist has been used to study its effect on the increase of tidal volumes in adult red-eared slider turtles (Trachemys scripta)[1].
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