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(±)-Verapamil hydrochloride

(±)-Verapamil hydrochloride
(±)-Verapamil hydrochloride
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Product Code : 540
Price And Quantity
  • Minimum Order Quantity
  • 1 Kilograms
  • Price
  • 100 Onwards INR
Product Specifications
  • Molecular Weight
  • 491.06
  • Molecular Formula
  • C27H39ClN2O4
  • Melting Point
  • 138-140�C
  • Usage
  • Treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.
  • Purity(%)
  • 99%
Product Description

(±)-Verapamil hydrochloride


  • Synonym: 5-[N-(3,4-Dimethoxyphenylethyl)methylamino]-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile hydrochloride

    • Linear Formula: (CH3O)2C6H3CH2CH2N(CH3)(CH2)3C[C6H3(OCH3)2][CH(CH3)2]CN · HCl

    • Molecular Weight: 491.06

    • CAS Number: 152-11-4

      assay  


      ¥99% (titration)
      form   powder
      color   white
      mp   142 °C (dec.)(lit.)
      solubility   methanol: soluble50 mg/mL
        ethanol: soluble
      originator   Pfizer
      Gene Information   human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)

      Description

      Packaging

      1, 5, 10 g in glass bottle

      Biochem/physiol Actions

      ±1-adrenoceptor antagonist; L-type calcium channel blocker. Blocks L-type Ca2+ channels in smooth and cardiac muscle, induces apoptosis of human primary and metastatic colon adenocarcinoma cells in vitro. Drug resistance reversal agent acting on Pgp, e.g. decrease renal tubule elimination of digoxin. Increases basal ATPase activity of Pgp. Substrate of Cyp3A4 and CYP2C6.

      Features and Benefits

      This compound is a featured product for ADME Tox research.

      This compound is also offered as part of Sigmas Library of Pharmacologically Active Compounds (LOPAC), a biologically annotated collection of high-quality, ready-to-screen compounds. 

      This compound is featured on the Calcium Channels page of the Handbook of Receptor Classification and Signal Transduction.

      This compound was developed by Pfizer.

       

Trade Information
  • Payment Terms
  • Cash in Advance (CID), Cash Advance (CA)
  • Supply Ability
  • 500 Kilograms KG Per Month
  • Delivery Time
  • 2-8 Week
  • Sample Available
  • Yes
  • Sample Policy
  • Sample costs shipping and taxes has to be paid by the buyer
  • Packaging Details
  • Carton and Poly Bag.
  • Main Export Market(s)
  • Africa, Middle East, Western Europe, Eastern Europe, South America, North America, Central America, Australia, Asia
  • Main Domestic Market
  • All India

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