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()-Verapamil hydrochloride

()-Verapamil hydrochloride

100 INR
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Product Details:

  • Usage Treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.
  • Melting Point 138-140C
  • Molecular Weight 491.06
  • Molecular Formula C27H39ClN2O4
  • Purity(%) 99%
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Price And Quantity

  • 1 Kilograms
  • 100 INR

Product Specifications

  • 138-140C
  • C27H39ClN2O4
  • Treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.
  • 99%
  • 491.06

Trade Information

  • Cash in Advance (CID) Cash Advance (CA)
  • 500 Kilograms KG Per Month
  • 2-8 Week
  • Yes
  • Sample costs shipping and taxes has to be paid by the buyer
  • Carton and Poly Bag.
  • Western Europe Australia Eastern Europe Central America Africa Middle East South America Asia North America
  • All India

Product Description

(±)-Verapamil hydrochloride


  • Synonym: 5-[N-(3,4-Dimethoxyphenylethyl)methylamino]-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile hydrochloride

    • Linear Formula: (CH3O)2C6H3CH2CH2N(CH3)(CH2)3C[C6H3(OCH3)2][CH(CH3)2]CN · HCl

    • Molecular Weight: 491.06

    • CAS Number: 152-11-4

      assay  


      		¥99% (titration)
      form   powder
      color   white
      mp   142 °C (dec.)(lit.)
      solubility   methanol: soluble50 mg/mL
        ethanol: soluble
      originator   Pfizer
      Gene Information   human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)

      Description

      Packaging

      1, 5, 10 g in glass bottle

      Biochem/physiol Actions

      ±1-adrenoceptor antagonist; L-type calcium channel blocker. Blocks L-type Ca2+ channels in smooth and cardiac muscle, induces apoptosis of human primary and metastatic colon adenocarcinoma cells in vitro. Drug resistance reversal agent acting on Pgp, e.g. decrease renal tubule elimination of digoxin. Increases basal ATPase activity of Pgp. Substrate of Cyp3A4 and CYP2C6.

      Features and Benefits

      This compound is a featured product for ADME Tox research.

      This compound is also offered as part of Sigmas Library of Pharmacologically Active Compounds (LOPAC), a biologically annotated collection of high-quality, ready-to-screen compounds. 

      This compound is featured on the Calcium Channels page of the Handbook of Receptor Classification and Signal Transduction.

      This compound was developed by Pfizer.

       

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