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(Z)-Guggulsterone

(Z)-Guggulsterone
(Z)-Guggulsterone
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Product Code : 193
Product Description

(Z)-Guggulsterone

Analytical standard

Synonym: (17Z)-Pregna-4,17(20)-diene-3,16-dione, 4,17(20)-trans-Pregnadiene-3,16-dione

  • CAS Number 39025-23-5

  • Empirical Formula (Hill Notation) C21H28O2

  • Molecular Weight 312.45

grade   analytical standard
assay   ≥95.0% (HPLC)
form   neat
shelf life   limited shelf life, expiry date on the label
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
format   neat

Biochem/physiol Actions

(Z)-Guggulsterone is a natural product that lowers cholesterol due to its function as an antagonist ligand for the bile acid receptor. (Z)-Guggulsterone is a nuclear hormone receptor that regulates the transcription of several genes involved in cholesterol metabolism and plays a role in cholesterol level regulation. (Z)-Guggulsterone is also a selective farnesoid X receptor (FXR) modulator.

 


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