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12(S)-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid

12(S)-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid

Product Details:

  • Density 0.943 g/cm3
  • Molecular Formula C20H32O2
  • Melting Point −44 C (−47 F; 229 K)
  • Boiling point 468.914.0 C at 760 mmHg
  • Molecular Weight 304.5 Grams (g)
  • Chemical Name 12(S)-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid
  • Purity(%) 98%
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12(S)-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid Price And Quantity

  • 1 Kilograms
  • 100 INR

12(S)-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid Product Specifications

  • −44 C (−47 F; 229 K)
  • 98%
  • 468.914.0 C at 760 mmHg
  • 0.943 g/cm3
  • C20H32O2
  • 304.5 Grams (g)
  • 12(S)-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid

12(S)-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid Trade Information

  • Cash in Advance (CID) Cash Advance (CA)
  • 500 Kilograms Per Month
  • 3-4 Week
  • Yes
  • Sample costs shipping and taxes has to be paid by the buyer
  • North America Middle East Africa Western Europe Eastern Europe South America Asia Central America Australia
  • All India

Product Description

12(S)-Hydroxy-(5z,8z,10e,14z)-Eicosatetraenoic Acid

  • Synonym: (S)-12-HETE

    • Empirical Formula (Hill Notation): c20h32o3

    • Molecular Weight: 320.47

    • Cas Number: 54397-83-0

Properties



Assay  

95% (HPLC)

Concentration  

~100 g/mL In Ethanol

Shipped In  

Dry Ice

Storage Temp.  

20C


Description

Biochem/Physiol Actions

Prometastatic Metabolite Of Arachidonic Acid Via The 12-Lipoxygenase Pathway That Is Expressed In Many Tumor Cell Lines. It Is Produced In Coronary Microvasculature And Is A Potent Inducer Of Relaxation And Hyperpolarization Of These Microvessels. It Activates Large-Conductance Ca2+-Activated K+ Currents In Coronary Microvascular Smooth Muscle.

12(S)-Hete Is A Bioactive Lipid Implicated In Angiogenesis, Growth, And Metastasic Action In Tumor Cell Lines And In Animal Models. Arachidonate 12-Lipoxygenase (12-LOX) Converts Arachidonic Acid To 12(S)-(Hete). Alteration In 12-Lox Expression Or Activity Has Been Reported In Various Carcinomas Including Prostate Carcinoma.

Packaging

Packaged Under Argon.

Other Notes

Tandem Mass Spectrometry Data Independently Generated By Scripps Center For Metabolomics Is Available To View Or Download In Pdf. H7768.Pdf Tested Metabolites Are Featured On Scripps Center For Metabolomics Metlin Metabolite Database. To Learn More, Visit Sigma.Com/Metlin.



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