12(S)-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid

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12(S)-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid Specification

Molecular Formula
C20H32O2

Melting Point
44 C

Density
0.943 Gram per cubic centimeter(g/cm3)

Shelf Life
12 Months

Boiling point
468.9

Molecular Weight
304.5 Grams (g)

CAS No
54397-83-0

Purity(%)
98%

12(S)-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid Trade Information

Minimum Order Quantity
1 Kilograms

Payment Terms
Cash in Advance (CID), Cash Advance (CA)

Supply Ability
500 Kilograms Per Month

Delivery Time
3-4 Week

Sample Available
Yes

Sample Policy
Sample costs shipping and taxes has to be paid by the buyer

Main Export Market(s)
North America, Middle East, Africa, Western Europe, Eastern Europe, South America, Asia, Central America, Australia

Main Domestic Market
All India

About 12(S)-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid

12(S)-Hydroxy-(5z,8z,10e,14z)-Eicosatetraenoic Acid Synonym: (S)-12-HETE Empirical Formula (Hill Notation): c20h32o3 Molecular Weight: 320.47 Cas Number: 54397-83-0 Properties Assay 95% (HPLC) Concentration 100g/mL In Ethanol Shipped In Dry Ice Storage Temp. 20 Degree C Description Biochem/Physiol Actions Prometastatic Metabolite Of Arachidonic Acid Via The 12-Lipoxygenase Pathway That Is Expressed In Many Tumor Cell Lines. It Is Produced In Coronary Microvasculature And Is A Potent Inducer Of Relaxation And Hyperpolarization Of These Microvessels. It Activates Large-Conductance Ca2+-Activated K+ Currents In Coronary Microvascular Smooth Muscle. 12(S)-Hete Is A Bioactive Lipid Implicated In Angiogenesis, Growth, And Metastasic Action In Tumor Cell Lines And In Animal Models. Arachidonate 12-Lipoxygenase (12-LOX) Converts Arachidonic Acid To 12(S)-(Hete). Alteration In 12-Lox Expression Or Activity Has Been Reported In Various Carcinomas Including Prostate Carcinoma. Packaging Packaged Under Argon. Other Notes Tandem Mass Spectrometry Data Independently Generated By Scripps Center For Metabolomics Is Available To View Or Download In Pdf. H7768.Pdf Tested Metabolites Are Featured On Scripps Center For Metabolomics Metlin Metabolite Database. To Learn More, Visit Sigma.Com/Metlin.