2,5-Dimethyl-celecoxib

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MOQ : 1 Kilograms

2,5-Dimethyl-celecoxib Specification

Solubility
DMSO: 20 mg/mL

Purity
98%

Molecular Formula
C18H16F3N3O2S

Usage
Celecoxib, sold under the brand name Celebrex among others, is a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID). It is used to treat the pain and inflammation in osteoarthritis, acute pain in adults, rheumatoid arthritis, ankylosing spondylitis, painful menstruation, and juvenile rheumatoid arthritis.

Molecular Weight
395.4 Grams (g)

Physical Form
Powder

2,5-Dimethyl-celecoxib Trade Information

Minimum Order Quantity
1 Kilograms

Payment Terms
Cash in Advance (CID), Cash Advance (CA)

Supply Ability
500 Kilograms KG Per Month

Delivery Time
2-8 Week

Sample Available
Yes

Sample Policy
Sample costs shipping and taxes has to be paid by the buyer

Packaging Details
Carton and Poly Bag.

Main Export Market(s)
Western Europe, Central America, Eastern Europe, Africa, Middle East, South America, Australia, Asia, North America

Main Domestic Market
All India

About 2,5-Dimethyl-celecoxib

2,5-Dimethyl-celecoxib VETRANAL, analytical standard Synonym: 2,5-Dimethylcelecoxib, 4-[5-(2,5-dimethylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-benzenesulfonamide CAS Number 457639-26-8 Empirical Formula (Hill Notation) C18H16F3N3O2S Molecular Weight 395.40 grade analytical standard product line VETRANAL form neat application(s) HPLC: suitable gas chromatography (GC): suitable format neat Biochem/physiol Actions Celecoxib, and the inactive analog 2,5-dimethyl celecoxib both induce apoptosis in a many cancer cell lines by down-regulating the expression of survivin. This activiy is mediated via an AKT mediated pathway, and is unique to this class of cyclo-oxygenase inhibitors, as non-selective NSAIDs or other COX-2 specific inhibitors such as rofecoxib, do not effect survivin expression. Unlike celecoxib, 2,5-dimethyl celecoxib is devoid of any inhibitory activity against COX-2.

FAQs of 2,5-Dimethyl-celecoxib:

Q: What is the physical form of 2,5-Dimethyl-celecoxib?

A: The physical form of 2,5-Dimethyl-celecoxib is powder.

Q: What is the solubility of 2,5-Dimethyl-celecoxib?

A: 2,5-Dimethyl-celecoxib is soluble in DMSO at 20 mg/mL.

Q: What is the molecular weight of 2,5-Dimethyl-celecoxib?

A: The molecular weight of 2,5-Dimethyl-celecoxib is 395.4 grams (g).

Q: What is the purity of 2,5-Dimethyl-celecoxib?

A: The purity of 2,5-Dimethyl-celecoxib is 98%.

Q: What is the molecular formula of 2,5-Dimethyl-celecoxib?

A: The molecular formula of 2,5-Dimethyl-celecoxib is C18H16F3N3O2S.

Q: How is 2,5-Dimethyl-celecoxib used?

A: 2,5-Dimethyl-celecoxib is a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation in osteoarthritis, acute pain, rheumatoid arthritis, ankylosing spondylitis, painful menstruation, and juvenile rheumatoid arthritis.