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2,5-Dimethyl-celecoxib

2,5-Dimethyl-celecoxib
2,5-Dimethyl-celecoxib
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Product Code : 562
Price And Quantity
  • Minimum Order Quantity
  • 1
  • Unit of Measure
  • Kilograms/Kilograms
  • Price Range
  • 500.00 - 1500.00 USD ($)
Product Specifications
  • Purity
  • 98%
  • Molecular Formula
  • C18H16F3N3O2S
  • Molecular Weight
  • 395.4 Grams (g)
  • Physical Form
  • Powder
  • Solubility
  • ‎DMSO: 20 mg/mL
  • Usage
  • Celecoxib, sold under the brand name Celebrex among others, is a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID). It is used to treat the pain and inflammation in osteoarthritis, acute pain in adults, rheumatoid arthritis, ankylosing spondylitis, painful menstruation, and juvenile rheumatoid arthritis.
Product Description

2,5-Dimethyl-celecoxib

VETRANAL, analytical standard

Synonym: 2,5-Dimethylcelecoxib, 4-[5-(2,5-dimethylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-benzenesulfonamide

  • CAS Number 457639-26-8
  • Empirical Formula (Hill Notation) C18H16F3N3O2S
  • Molecular Weight 395.40
  •  

    grade   analytical standard
    product line   VETRANAL
    form   neat
    application(s)   HPLC: suitable
      gas chromatography (GC): suitable
    format   neat

    Biochem/physiol Actions

    Celecoxib, and the inactive analog 2′,5′-dimethyl celecoxib both induce apoptosis in a many cancer cell lines by down-regulating the expression of survivin. This activiy is mediated via an AKT mediated pathway, and is unique to this class of cyclo-oxygenase inhibitors, as non-selective NSAIDs or other COX-2 specific inhibitors such as rofecoxib, do not effect survivin expression. Unlike celecoxib, 2′,5′-dimethyl celecoxib is devoid of any inhibitory activity against COX-2.

     

    Trade Information
    • Payment Terms
    • Cash in Advance (CID), Cash Advance (CA)
    • Supply Ability
    • 500 KG Per Month
    • Delivery Time
    • 2-8 Week
    • Sample Available
    • Yes
    • Sample Policy
    • Sample costs shipping and taxes has to be paid by the buyer
    • Packaging Details
    • Carton and Poly Bag.
    • Main Domestic Market
    • All India

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