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2,5-Dimethyl-celecoxib

2,5-Dimethyl-celecoxib

100 Onwards INR
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Product Details:

  • Physical Form Powder
  • Purity 98%
  • Molecular Weight 395.4 Grams (g)
  • Molecular Formula C18H16F3N3O2S
  • Usage Celecoxib, sold under the brand name Celebrex among others, is a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID). It is used to treat the pain and inflammation in osteoarthritis, acute pain in adults, rheumatoid arthritis, ankylosing spondylitis, painful menstruation, and juvenile rheumatoid arthritis.
  • Solubility DMSO: 20 mg/mL
  • Supply Ability : 500 Kilograms KG Per Month
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Price And Quantity

  • 1 Kilograms
  • 100 Onwards INR

Product Specifications

  • DMSO: 20 mg/mL
  • 395.4 Grams (g)
  • Powder
  • 98%
  • C18H16F3N3O2S
  • Celecoxib, sold under the brand name Celebrex among others, is a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID). It is used to treat the pain and inflammation in osteoarthritis, acute pain in adults, rheumatoid arthritis, ankylosing spondylitis, painful menstruation, and juvenile rheumatoid arthritis.

Trade Information

  • Cash in Advance (CID), Cash Advance (CA)
  • 500 Kilograms KG Per Month
  • 2-8 Week
  • Yes
  • Sample costs shipping and taxes has to be paid by the buyer
  • Carton and Poly Bag.
  • Africa, Middle East, Western Europe, Eastern Europe, South America, North America, Central America, Australia, Asia
  • All India

Product Description

2,5-Dimethyl-celecoxib

VETRANAL, analytical standard

Synonym: 2,5-Dimethylcelecoxib, 4-[5-(2,5-dimethylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-benzenesulfonamide

  • CAS Number 457639-26-8
  • Empirical Formula (Hill Notation) C18H16F3N3O2S
  • Molecular Weight 395.40

    •  

    grade   analytical standard
    product line   VETRANAL
    form   neat
    application(s)   HPLC: suitable
      gas chromatography (GC): suitable
    format   neat

    Biochem/physiol Actions

    Celecoxib, and the inactive analog 2,5-dimethyl celecoxib both induce apoptosis in a many cancer cell lines by down-regulating the expression of survivin. This activiy is mediated via an AKT mediated pathway, and is unique to this class of cyclo-oxygenase inhibitors, as non-selective NSAIDs or other COX-2 specific inhibitors such as rofecoxib, do not effect survivin expression. Unlike celecoxib, 2,5-dimethyl celecoxib is devoid of any inhibitory activity against COX-2.

     


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