About 2- [(RS)-(4-Methylphenyl)phenylmethoxy]-N,N-dimethylethanamine hydrochloride

2-[(RS)-(4-Methylphenyl)phenylmethoxy]-N,N-dimethylethanamine hydrochloride

pharmaceutical impurity standard

Synonym: 2-[(4-Methyl--phenylbenzyl)oxy]ethyl(dimethyl)ammonium chloride, 4-Methyldiphenhydramine hydrochloride, N,N-Dimethyl-2-[(4-methylphenyl)phenylmethoxy]ethanamin hydrochloride, Diphenhydramine impurity B (PhEur), Neobenodine

CAS Number 4024-34-4

Empirical Formula (Hill Notation) C₁₈H₂₃NO HCl

Molecular Weight 305.84

 

assay	98.0% (HPLC)
shelf life	limited shelf life, expiry date on the label
impurities	0.5% water

 

Physical and Chemical Properties

This compound presents as a white to off-white crystalline powder, notable for its hygroscopic characteristics and lack of odor. It freely dissolves in water, ethanol, and methanol. The solid decomposes before boiling and has a melting point in the range of 154158C. Suitable for laboratory and pharmaceutical applications, it meets a purity specification of greater than 98%.


Safe Handling and Storage

While not classified as hazardous under the GHS, exposure precautions are recommended. Users should wear personal protective equipment and avoid contact with eyes and skin. The substance should be kept tightly sealed in a cool, dry environment, protected from light. Correct storage ensures its quality remains intact for its 2-year shelf life.


Applications and Usage

This material is primarily used as a pharmaceutical intermediate and laboratory reagent. Researchers utilize it in the synthesis of active pharmaceutical ingredients (APIs) and related research tasks. Its high purity and solubility make it ideal for reliable experimental outcomes. The compound is supplied for research and pharmaceutical synthesis purposes only.