6-Amino-1- methyluracil

About 6-Amino-1- methyluracil

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·        6-Amino-5-(N-methylformylamino)-1-methyluracil

Molecularformula: C…H‡NO

CASnumber: 2434-53-9

Appearance:White to off-white powder

Meltingpoint: 240-242C

solubility:Soluble in water, methanol, ethanol, and acetone

Stability:Stable at room temperature

Toxicity:Low toxicity

6-Amino-1-methyluracilis a synthetic pyrimidine derivative that is used as a research tool inbiochemistry and molecular biology. It is also being investigated as apotential cancer treatment.

It is astructural analog of uracil, a natural pyrimidine base found in DNA and RNA.

It is acompetitive inhibitor of the enzyme thymidylate synthase, which is involved inDNA synthesis.

Thisinhibition can lead to cell death in cancer cells.