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n-Butyl Lithium(2.5 M in Hexane)

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n-Butyl Lithium(2.5 M in Hexane) Specification

Ph Level
Strongly basic (pH unavailable for nonaqueous solution)

Boiling point
Hexane solvent: 68.7 C

CAS No
109-72-8

Packaging Type
Glass bottle, ampoule

Usage
As a strong base and nucleophile in organic synthesis

Physical State
Liquid

Flash Point
-22 C

Size
Custom packaging sizes available (standard: 100 mL, 250 mL, 500 mL)

Storage Instructions
Store under inert atmosphere, in cool, dry place, tightly sealed

Purity
2.5 M Solution in Hexane

Melting Point
-70 C

Density
0.68 Gram per cubic centimeter(g/cm3)

Molecular Weight
64.06 g/mol

Molecular Formula
C4H9Li

Shelf Life
12 months

Grade
Reagent Grade

Type
Solution

Application
Organic synthesis, polymerization initiator, chemical reagent

Appearance
Colorless to pale yellow liquid

Purity(%)
97%

Odor
Petroleum-like odor

Reactivity
Highly reactive with water, acids, and oxidizing agents

Stability
Sensitive to air and moisture

Transport Packaging
Packed under nitrogen in sealed containers

Solvent
Hexane, anhydrous

Regulatory Information
Complies with REACH and TSCA

Synonyms
n-Butyllithium, Butyllithium

Concentration
2.5 M in hexane

Toxicity
Toxic if inhaled, swallowed, or in contact with skin

Hazard Class
Flammable liquid, pyrophoric

UN Number
UN 3394

DOT Hazard Class
4.2 (Pyrophoric material)

Handling Precautions
Use only in inert atmosphere, avoid contact with skin and eyes

Autoignition Temperature
190 °C

n-Butyl Lithium(2.5 M in Hexane) Trade Information

Minimum Order Quantity
1 Piece

Payment Terms
Cash in Advance (CID), Cash Advance (CA)

Supply Ability
3 Pieces Per Week

Delivery Time
3-4 Week

Main Export Market(s)
Australia, North America, South America, Middle East, Africa, Central America, Western Europe, Asia, Eastern Europe

Main Domestic Market
All India

Certifications
ISO 9001: 2015 CERTIFICATE

About n-Butyl Lithium(2.5 M in Hexane)

n-Butyllithium solution

2.5 M in hexanes

Synonym: n-BuLi, Butyl lithium, Butyllithium solution, Lithium-1-butanide

CAS Number109-72-8
Linear Formula CH₃(CH₂)₃Li
Molecular Weight 64.06

Quality Level	200
form	liquid
concentration	2.5 M in hexanes
density	0.693 g/mL at 25 C
storage temp.	2-8C

Powerful Reagent for Synthetic Applications

n-Butyl Lithium (2.5 M in Hexane) stands out for its strong basicity and nucleophilicity, making it essential for various organic synthesis and polymerization reactions. Its reliable activity ensures efficient reaction initiation and substrate deprotonation, which is particularly useful in the pharmaceutical, academic, and industrial laboratories focused on advanced organic chemistry.

Safe Handling and Storage Guidelines

Due to its high reactivity and pyrophoric nature, n-Butyl Lithium must always be handled under an inert atmosphere, such as nitrogen or argon. The solution is supplied anhydrous, packed in sealed glass containers or ampoules to prevent exposure to air and moisture. Store in a cool, dry place, tightly sealed, and follow all safety protocols when transferring or using the reagent.

FAQ's of n-Butyl Lithium(2.5 M in Hexane):

Q: How should n-Butyl Lithium (2.5 M in Hexane) be handled for laboratory use?

A: Always handle n-Butyl Lithium under an inert atmosphere, such as nitrogen or argon, using appropriate personal protective equipment. Avoid contact with skin, eyes, and moisture to prevent hazardous reactions. Use only in a well-ventilated fume hood, and follow institutional safety guidelines.

Q: What are the primary uses of n-Butyl Lithium in organic synthesis?

A: This reagent acts as a strong base and nucleophile in organic synthesis, enabling deprotonation, alkyl lithium compound preparation, and initiation of polymerization processes. It is widely employed in research, pharmaceuticals, and chemical manufacturing for these purposes.

Q: When does the n-Butyl Lithium solution begin to lose effectiveness, and how can this be prevented?

A: n-Butyl Lithium typically has a shelf life of 12 months when stored properly under inert atmosphere and tightly sealed. Exposure to moisture, air, or prolonged storage at room temperature can degrade its effectiveness, so always store it according to label instructions.

Q: Where should n-Butyl Lithium (2.5 M in Hexane) be stored to maintain stability?

A: Store the solution in a cool, dry place away from sources of ignition, air, and moisture. Keep containers sealed, under inert gas such as nitrogen, and in an area designated for pyrophoric materials. This prevents decomposition and autoignition.

Q: What is the process for safe disposal of n-Butyl Lithium residue?

A: Dispose of residues by carefully quenching remaining n-Butyl Lithium under inert atmosphere with a suitable alcohol (such as isopropanol) in a controlled manner. Follow local regulations and institutional hazardous waste disposal policies.

Q: What are the principal hazards associated with n-Butyl Lithium (2.5 M in Hexane)?

A: n-Butyl Lithium is classified as a flammable, pyrophoric liquid and is highly toxic if swallowed, inhaled, or in contact with skin. It can spontaneously ignite in air and reacts violently with water, acids, and oxidizing agents. Always prioritize safety.

Q: What benefits does using n-Butyl Lithium offer for organic synthesis and research?

A: Its high purity, strong basicity, and nucleophilicity provide consistent results in various advanced syntheses, notably enabling efficient and selective reactions. This reagent supports demanding research and manufacturing needs in academia and industry.

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