Periodic acid is an inorganic acid commonly used as an oxidizing agent. Periodic acid oxidation is one of the steps in the periodate-resorcinol assay, used in the determination of sialic acid.Periodic acid reacts with 1,2 glycol linkage of carbohydrates to form aldehydes which can be stained by Schiffs reagent. Therefore periodic-acid-Schiffs reagent (PAS) is used in histochemistry to determine carbohydrates in tissue sections.
Periodic acid may be used in the following reactions:
Oxidation of alcohols to ketones and aldehydes.
Oxidation hydroxylamine derivatives.
Oxidation of arenes to quinones
Deprotection of the dithio- and oxathio-derivatives.
Oxidative degradation of epoxidized natural rubber (ENR).
Oxidation of urazoles and bis-urazoles to triazolinediones.
Oxidative cleavage of glucosazone
|99.0-101.0% (ACS specification)|
|0.01% other halogens|
|mp||122 C (lit.)|
|anion traces||sulfate (SO42-): 0.01%|
|cation traces||Fe: 0.003%|
|heavy metals: 0.005%|
CAS Number 10450-60-9
Empirical Formula (Hill Notation) H5IO6
Molecular Weight 227.94
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