()--Lipoic acid

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MOQ : 1 Kilograms

()--Lipoic acid Specification

Physical Form
Powder

Molecular Formula
C8H14O2S2

Chemical Name
Lipoic acid

()--Lipoic acid Trade Information

Minimum Order Quantity
1 Kilograms

Payment Terms
Cash in Advance (CID), Cash Advance (CA)

Supply Ability
500 Kilograms KG Per Month

Delivery Time
2-8 Week

Sample Available
Yes

Sample Policy
Sample costs shipping and taxes has to be paid by the buyer

Main Export Market(s)
Australia, Central America, Africa, Middle East, South America, Western Europe, Asia, Eastern Europe, North America

Main Domestic Market
All India

About ()--Lipoic acid

()--Lipoic acid

Synonym: ()-1,2-Dithiolane-3-pentanoic acid, 6,8-Dithiooctanoic acid, DL--Lipoic acid, DL-6,8-Thioctic acid, Lip(S₂)
- Empirical Formula (Hill Notation): C₈H₁₄O₂S₂
- Molecular Weight: 206.33
- CAS Number: 1077-28-7

biological source

	synthetic
description	Oxidized form
assay	99% (titration)
form	powder
solubility	ethanol: soluble50 mg/mL
Gene Information	human ... ACHE(43), BCHE(590) rat ... Adra1a(29412), Adra1b(24173), Adra1d(29413)

Description

Packaging

1, 5, 25, 50 g in poly bottle

500 mg in poly bottle

Preparation Note

()--Lipoic acid (-LA) is soluble in ethanol at 50 mg/ml

Application

-LA can reinstate endothelial activities and alleviate oxidative stress in high-fat fed diabetic rats⁴. It has also been used to analyze ROS production in astrocytes⁵.

Biochem/physiol Actions

Antioxidant and coenzyme needed for the activity of enzyme complexes such as those of pyruvate dehydrogenase and glycine decarboxylase. Exogenous thioctic acid is reduced intracellularly by two or more enzymes. The reduced form then influences a number of cell processes by direct radical scavenging, recycling of other antioxidants, increasing glutathione synthesis, and modulating transcription factor activity particularly that of NF-B. Decreases the phagocytosis of myelin by macrophages.

Features and Benefits

This compound is also offered as part of Sigmas Library of Pharmacologically Active Compounds (LOPAC¹²⁸⁰), a biologically annotated collection of high-quality, ready-to-screen compounds.

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