(+)-Thalidomide

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MOQ : 1 Kilograms

(+)-Thalidomide Specification

Appearance
White Solid

Molecular Weight
258.23

Molecular Formula
C13H10N2O4

Melting Point
273-276°C

Density
1.6±0.1 g/cm3

Chemical Name
(+)-Thalidomide

Purity(%)
99%

(+)-Thalidomide Trade Information

Minimum Order Quantity
1 Kilograms

Payment Terms
Cash in Advance (CID), Cash Advance (CA)

Supply Ability
500 Kilograms KG Per Month

Delivery Time
2-8 Week

Sample Available
Yes

Sample Policy
Sample costs shipping and taxes has to be paid by the buyer

Packaging Details
Carton and Poly Bag.

Main Export Market(s)
Western Europe, Central America, Africa, Middle East, South America, Australia, Asia, Eastern Europe, North America

Main Domestic Market
All India

About (+)-Thalidomide

(+)-Thalidomide Synonym: R-(+)-2-(2,6-Dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione Empirical Formula (Hill Notation): C13H10N2O4Molecular Weight: 258.23CAS Number: 2614-06-4 assay 98% (HPLC) form powder color white to beige solubility DMSO: soluble15mg/mL, clear originator Celgene storage temp. room temp Gene Information human ... LITAF(9516), TNF(7124)mouse ... Nos2(18126)rat ... Nos1(24598) Description Biochem/physiol Actions (-)-Thalidomide selectively inhibits biosynthesis of tumor necrosis factor (TNF-). (R)-Thalidomide is called "safe enantiomer", but it can be converted in the body to (S)-isomer. Preparation Note Thalidomide is soluble in DMSO at a concentration that is greater than or equal to 20 mg/ml. It is insoluble in ethanol and water. Application Thalidomide has been used to study its teratogenic effects in chicken embryos and human embryonic cells. This study reported that thalidomide causes limb defects by stabilizing PTEN, inhibiting the expression of Akt and activating caspase-dependent apoptosis[1]. Thalidomide has also been used for studying glutathione mediated teratogenic resistance in mouse embryos[2]. Features and Benefits This compound was developed by Celgene.