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Aloe-emodin

Aloe-emodin
Aloe-emodin
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Product Code : 1767
Product Description

Aloe-emodin

analytical standard

Synonym: 1,8-Dihydroxy-3-(hydroxymethyl)anthraquinone, 3-Hydroxymethylchrysazine

  • CAS Number 481-72-1

  • Empirical Formula (Hill Notation) C15H10O5

  • Molecular Weight 270.24

Properties



grade   analytical standard
assay   ≥97.0% (HPLC)
form   neat
shelf life   limited shelf life, expiry date on the label
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
format   neat
storage temp.   2-8°C

Description

Biochem/physiol Actions

Laxative/cathartic compound; increases the contraction of intestinal smooth muscle by releasing endogenous acetylcholine. Anti-tumor activity is associated with an increased production of reactive oxygen species (ROS) that, in turn, reduces the mitochondrial transmembrane electrical potential, thus inducing a permeability transition that sets in motion a series of events culminating in cellular apoptosis. Genotoxicity and mutagenicity appear to be due to the inhibition of topoisomerase II activity by aloe emodin.


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