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CAS Number 481-72-1
Empirical Formula (Hill Notation) C15H10O5
Molecular Weight 270.24
|shelf life||limited shelf life, expiry date on the label|
|gas chromatography (GC): suitable|
Laxative/cathartic compound; increases the contraction of intestinal smooth muscle by releasing endogenous acetylcholine. Anti-tumor activity is associated with an increased production of reactive oxygen species (ROS) that, in turn, reduces the mitochondrial transmembrane electrical potential, thus inducing a permeability transition that sets in motion a series of events culminating in cellular apoptosis. Genotoxicity and mutagenicity appear to be due to the inhibition of topoisomerase II activity by aloe emodin.