Aloe-emodin

About Aloe-emodin

Aloe-emodin analytical standard Synonym: 1,8-Dihydroxy-3-(hydroxymethyl)anthraquinone, 3-Hydroxymethylchrysazine CAS Number 481-72-1 Empirical Formula (Hill Notation) C15H10O5 Molecular Weight 270.24 Properties grade analytical standard assay 97.0% (HPLC) form neat shelf life limited shelf life, expiry date on the label application(s) HPLC: suitable gas chromatography (GC): suitable format neat storage temp. 2-8C Description Biochem/physiol Actions Laxative/cathartic compound; increases the contraction of intestinal smooth muscle by releasing endogenous acetylcholine. Anti-tumor activity is associated with an increased production of reactive oxygen species (ROS) that, in turn, reduces the mitochondrial transmembrane electrical potential, thus inducing a permeability transition that sets in motion a series of events culminating in cellular apoptosis. Genotoxicity and mutagenicity appear to be due to the inhibition of topoisomerase II activity by aloe emodin.