About Trifluoroacetic acid
Trifluoroacetic acid (TFA) is a widely used chemical renowned for its versatility and precision in various applications. Featuring a molecular formula of C2HF3O2 and a molecular weight of 114.02 grams, TFA exhibits exceptional qualities as a solvent and reagent. With a melting point of -15.4 C, it is miscible in numerous solutions, ensuring compatibility across diverse environments. Frequently employed in the synthesis of other chemicals and in analytical research, TFA serves as a vital ion-pairing agent in High-Performance Liquid Chromatography (HPLC), particularly for analyzing organic compounds such as peptides and small proteins. Furthermore, its adaptability as a solvent makes it suitable for nuclear magnetic resonance (NMR) spectroscopy when working with acid-stable substances.
FAQs of Trifluoroacetic acid:
Q: What is the primary usage of Trifluoroacetic acid?
A: Trifluoroacetic acid is primarily used to make other chemicals, as a solvent, and as an ion-pairing agent in HPLC for analyzing peptides and small proteins.
Q: Can Trifluoroacetic acid be used in NMR spectroscopy?
A: Yes, TFA is a versatile solvent for NMR spectroscopy, provided the materials are stable in acidic conditions.
Q: What is the molecular weight of Trifluoroacetic acid?
A: The molecular weight of Trifluoroacetic acid is 114.02 grams.
Q: Is Trifluoroacetic acid fully miscible in solutions?
A: Yes, Trifluoroacetic acid is miscible, ensuring compatibility with various solvents.
Q: At what temperature does Trifluoroacetic acid melt?
A: The melting point of Trifluoroacetic acid is -15.4 C.