benecel XR and XRF HPMC controlled release matrix formers

Price 100 INR/ Piece

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MOQ : 1 Piece

benecel XR and XRF HPMC controlled release matrix formers Specification

Density
0.80 Gram per cubic centimeter(g/cm3)

Ph Level
Neutral (6.5 - 8.0) in 2% aqueous solution

Melting Point
Non-melting, decomposes above 200C

Storage Instructions
Store in a cool, dry place, tightly sealed

Molecular Formula
C12H20O10

Size
Available in various particle sizes (fine to coarse)

CAS No
9004-65-3

Shelf Life
At least 36 months under recommended storage conditions

Usage
Direct compression excipient and sustained release matrix

Molecular Weight
Approximately 86,000 g/mol (varies by viscosity grade)

Physical State
Solid powder

Packaging Type
HDPE drum, bag-in-box

Grade
Pharmaceutical Grade

Type
Hydroxypropyl Methylcellulose (HPMC)

Application
Controlled release matrix former for oral solid dosage forms

Appearance
White to off-white powder

Purity(%)
>99%

benecel XR and XRF HPMC controlled release matrix formers Trade Information

Minimum Order Quantity
1 Piece

Payment Terms
Cash in Advance (CID), Cash Advance (CA)

Supply Ability
3 Pieces Per Week

Main Export Market(s)
Western Europe, Eastern Europe, Central America, Middle East, South America, Asia, North America, Australia, Africa

About benecel XR and XRF HPMC controlled release matrix formers

benecel XR and XRF HPMC controlled release matrix formers

enhanced controlled release technology for improved strengthand flowability

description Benecel XR and XRF are HPMC products withoptimized polymer structure and particle morphology that enable the formulationof safe, effective, and robust oral solid controlled-release dose forms.

key features and benefits optimized polymer structure andparticle morphology: provides better powder flowability and improved tabletstrength better compactibility at high tableting speed: produces robusttablets under high-throughput during large-scale tableting operations consistent particle size distribution and bulk density: provides better powderflowability, better content uniformity, and lower tablet weight variability finer particle size grades (XRF): are designed for even higher tablet strengthand improved controlled-release profile available at four viscosity levels:K4M, K15M, K100M, and K200M providing a wide range of dissolution profiles

Superior Controlled Release Performance

Benecel XR and XRF provide precise control over drug release rates, supported by their reliable viscosity profiles and robust matrix-forming properties. This ensures patients receive medications at a consistent, controlled pace, contributing to improved therapeutic outcomes and patient compliance.

Pharmaceutical Compliance and Safety

These HPMC matrix formers meet USP/NF standards, including requirements for identity, purity, residue on ignition, and low heavy metal content. Each batch is produced under rigorous quality control, offering peace of mind for formulators prioritizing patient safety and regulatory compliance.

Versatile Application in Formulation Development

Benecel XR and XRF are compatible with a wide range of APIs and can be used in various processing methods such as direct compression. Their solubility profile and range of available particle sizes make them highly adaptable for custom formulation approaches in sustained-release oral dosage forms.

FAQs of benecel XR and XRF HPMC controlled release matrix formers:

Q: How are Benecel XR and XRF HPMC matrix formers typically used in pharmaceutical manufacturing?

A: Benecel XR and XRF are primarily used as controlled release matrix formers in oral solid dosage formulations. They can be directly compressed with active pharmaceutical ingredients and other excipients to manufacture tablets that deliver drugs over an extended period.

Q: What are the key benefits of choosing Benecel XR and XRF for sustained release applications?

A: These HPMC polymers ensure a consistent drug release profile, high purity, and compatibility with many APIs. They also comply with major pharmacopeial standards, contributing to both product quality and regulatory approval ease.

Q: When should different viscosity grades of Benecel XR and XRF be selected?

A: The choice of viscosity grade (20,000100,000 cps) depends on the desired drug release rate and matrix integrity. Higher viscosity grades typically provide slower drug release, allowing formulators to tailor release kinetics to specific therapeutic needs.

Q: Where should Benecel XR and XRF be stored to ensure optimal stability?

A: Both products should be stored in a cool, dry environment with tightly sealed packaging, such as HDPE drums or bag-in-box containers. Proper storage preserves product quality and extends shelf life to at least 36 months.

Q: What is the typical process for incorporating Benecel XR and XRF into formulations?

A: These excipients are generally blended with APIs and other ingredients and used in direct compression to form tablets. Their uniform particle size and high solubility in cold water support efficient processing and even matrix formation.

Q: How does the compatibility of Benecel XR and XRF enhance formulation flexibility?

A: Benecel XR and XRF exhibit excellent compatibility with a wide range of active pharmaceutical ingredients, allowing formulators to develop various oral sustained release products without encountering excipient-drug interaction issues.

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